Auto Calculation of Genetic Diversity Measures Based on Molecular Markers Data

Document Type : Original Research Articles

Authors

1 department of biostatistics of molecular biology research& studies institute, assuit university

2 Department of information systems of computer and information Faculty, Assuit university, Egypt

3 Department of Genetics of Agriculture Faculty, Assuit University, Egypt

4 Department of mathematics of science Faculty, new valley university, Egypt.

Abstract

Ahmed Bader EL-Deen calc is a free computer software program that offers a simple interface for measuring genetic diversity to help researchers achieve accurate genetic diversity estimates to satisfy the demands of geneticists and breeders by using data from molecular markers. to easily calculate gene diversity (Gd) indices (such as polymorphism information content (PIC), resolving power (Rb), polymorphism percent (P%), the diversity index (Di), the molecular index (MI), observed heterozygosity (Ho), expected heterozygosity (He), and nucleotide diversity of the dominant and co-dominant markers’ Gd) by using an appropriate programming language (C-sharp) for the design. To evaluate our program, we collected data on different shapes of dominant and co-dominant molecular markers from other researchers and used them to compare the efficacy and, most commonly, for genetic diversity measures. For ease of interpretation, we presented the results in a tabular format. In conclusion, the computer-based solution can potentially reduce the time necessary for manual computations while simultaneously making data analysis simple.

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